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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Javier | SP | Philadelphia Liberty Reserves | 24 | 10/02/2038 | Villa Bruzual | VEN | Right | Right | 6' 0" | 180 lbs | - |
| Sandoval, Octávio | 3B | Philadelphia Liberty Reserves | 25 | 07/14/2037 | Chiclayo | PER | Right | Right | 6' 2" | 200 lbs | - |
| Santamarina, Doug | SP | Free Agent | 35 | 06/11/2027 | Belize | BLZ | Switch | Right | 6' 4" | 200 lbs | - |
| Scarlett, Cliff | RP | Tortolita Drummers | 34 | 03/23/2028 | Saskatoon | CAN | Right | Right | 6' 3" | 200 lbs | $2,283,600 |
| Schmidt, Wayne | 3B | Tortolita Drummers | 32 | 08/10/2030 | Eureka | USA | Right | Right | 6' 2" | 200 lbs | - |
| Segura, Domingo | 1B | Free Agent | 32 | 01/13/2031 | Los Angeles | USA | Left | Left | 6' 2" | 200 lbs | - |
| Shaw, Jerry | RP | Monongahela Monsters | 25 | 04/16/2037 | Pacific Grove | USA | Right | Right | 5' 10" | 175 lbs | - |
| Sheppard, Michael | RP | Calgary Lynx | 24 | 01/26/2038 | Douglasville | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shipko, Daniil | CL | Norfolk Pajaritos | 24 | 03/02/2038 | Klaipeda | LTU | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Peter | SP | Philadelphia Liberty Reserves | 23 | 03/31/2039 | Hoffman Estates | USA | Left | Left | 6' 2" | 200 lbs | $280,000 |
| Snow, Todd | SS | Free Agent | 28 | 06/04/2034 | Longmont | USA | Right | Right | 6' 0" | 190 lbs | - |
| Soto, Ángelo | LF | Philadelphia Liberty Reserves | 29 | 03/07/2033 | Turmero | VEN | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Sparks, Tom | RP | Sioux Falls Red Pandas | 26 | 08/05/2036 | Corpus Christi | USA | Right | Right | 6' 0" | 190 lbs | - |
| Spencer, William | RP | Philadelphia Liberty Reserves | 33 | 11/10/2029 | Boston | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Spilsbury, Bryan | C | Philadelphia Liberty Reserves | 34 | 11/25/2028 | South Ockendon | ENG | Switch | Right | 6' 3" | 205 lbs | $5,000,000 |
| Stanton, Arch | SP | Hartford Pride | 27 | 05/17/2035 | Holyoke | USA | Left | Left | 6' 4" | 205 lbs | $280,000 |
| Stinson, Hunter | RP | Austin Black Mambas | 33 | 10/28/2029 | Brooklyn | USA | Left | Left | 6' 2" | 200 lbs | - |
| Strijk, Sjelle | RF | Sioux Falls Red Pandas | 26 | 07/09/2036 | Cul De Sac | SIM | Left | Left | 6' 4" | 200 lbs | - |
| Stroud, Chris | RP | Florence Flamingos | 25 | 03/16/2037 | Los Angeles | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sullivan, Alan | SP | Florence Flamingos | 29 | 06/04/2033 | Houston | USA | Right | Right | 6' 7" | 210 lbs | - |
| Sullivan, Ron | C | Philadelphia Liberty Reserves | 30 | 02/21/2032 | Denver | USA | Left | Right | 5' 11" | 200 lbs | - |
| Suzuki, Hiroya | RP | Monongahela Monsters | 23 | 04/23/2039 | Fukaya | JPN | Right | Right | 6' 3" | 195 lbs | - |
| Suárez, José | RP | Florence Flamingos | 28 | 09/17/2034 | Huntington Beach | USA | Right | Right | 6' 2" | 200 lbs | - |
| Swanson, Joe | CF | Nashville Hot Chickens | 27 | 10/11/2035 | Denver | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sáenz, Juan | 1B | Sioux Falls Red Pandas | 30 | 11/25/2032 | New York | USA | Right | Right | 6' 2" | 205 lbs | - |
