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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saito, Hidekazu | RP | MSL Kingston Ponies | 17 | 10/22/2045 | Fukushima | JPN | Right | Right | 6' 2" | 175 lbs | - |
| Saito, Sosuke | SP | MSL Charleston Battery | 18 | 07/18/2044 | Shizunai | JPN | Right | Right | 6' 3" | 185 lbs | - |
| Salas, Francisco | SP | Free Agent | 20 | 04/26/2043 | San Mateo | VEN | Left | Left | 6' 1" | 165 lbs | - |
| Sam, Hong-chang | SP | MSL Thunder Bay Northern Lions BC | 18 | 02/20/2045 | Seoul | KOR | Right | Right | 6' 8" | 200 lbs | - |
| Sandoval, Jorge | SP | MSL Detroit Rock City | 18 | 08/10/2044 | Flores | GUA | Right | Right | 5' 9" | 155 lbs | - |
| Santos, Jaime | RP | MSL Kingston Ponies | 17 | 08/04/2045 | Santo Domingo | DOM | Left | Left | 6' 8" | 205 lbs | - |
| Santos, Martín | RP | Free Agent | 20 | 08/23/2042 | Santo Domingo | DOM | Left | Left | 5' 9" | 155 lbs | - |
| Sas, Riemer | CF | MSL Nova Scotia Leviathan | 18 | 07/08/2044 | Little Bay | SIM | Right | Left | 6' 3" | 185 lbs | - |
| Schultz, Brian | RF | MSL Baltimore Bullets | 18 | 07/03/2045 | Treasure Island | USA | Left | Left | 6' 0" | 175 lbs | - |
| Sekiguchi, Shigeru | 1B | Free Agent | 20 | 07/31/2042 | Ontario | USA | Right | Right | 6' 2" | 185 lbs | - |
| Seow, Jian-gun | RP | Free Agent | 19 | 11/29/2043 | Fengyuan | TPE | Switch | Right | 6' 2" | 180 lbs | - |
| Sheridan, Ryan | SP | MSL Oakland Oaks | 18 | 02/18/2045 | Romulus | USA | Right | Right | 6' 6" | 200 lbs | - |
| Sierra, José | SP | MSL Baltimore Bullets | 17 | 09/20/2045 | Cagua | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sim, Sang-chul | RP | MSL Oakland Oaks | 18 | 02/18/2045 | Suwon | KOR | Left | Left | 6' 4" | 190 lbs | - |
| Sims, Jeff | 1B | MSL Mexico City Blue Demons | 18 | 04/03/2045 | Garden City | USA | Left | Left | 6' 2" | 195 lbs | - |
| Sinke, Jerrel | SP | MSL Oakland Oaks | 18 | 10/27/2044 | Cole Bay | SIM | Right | Right | 6' 1" | 185 lbs | - |
| Skjold, Thomas | SP | MSL Kingston Ponies | 17 | 11/15/2045 | Oslo | NOR | Right | Right | 6' 8" | 205 lbs | - |
| Smith, Norman | SP | MSL Buckhead Bowties | 18 | 11/17/2044 | Mission Viejo | USA | Left | Right | 6' 4" | 195 lbs | - |
| Solano, Roberto | SP | MSL Nova Scotia Leviathan | 16 | 11/30/2046 | Caracas | VEN | Switch | Right | 6' 2" | 175 lbs | - |
| Somers, Mateo | RP | Free Agent | 20 | 09/29/2042 | Rijswijk | NED | Right | Right | 6' 5" | 200 lbs | - |
| Sousa, Ismael | SP | MSL Thunder Bay Northern Lions BC | 16 | 06/11/2047 | Caracas | VEN | Left | Left | 6' 2" | 170 lbs | - |
| Srskic, Sinisa | C | Free Agent | 20 | 06/07/2043 | Vukovar | CRO | Right | Right | 6' 1" | 190 lbs | - |
| Stamfordham, Jonathan | 2B | MSL Mexico City Blue Demons | 18 | 01/23/2045 | Oranjestad | ARU | Right | Right | 6' 1" | 180 lbs | - |
| Stewart, Brian | RP | MSL Oakland Oaks | 18 | 05/15/2045 | Baton Rouge | USA | Left | Right | 6' 5" | 195 lbs | - |
| Stewart, Ralph | SP | MSL Charleston Battery | 18 | 06/19/2045 | Tomball | USA | Left | Left | 6' 4" | 200 lbs | - |
| Sugiyama, Noburo | LF | MSL Cape Coral Hurricanes | 19 | 06/14/2044 | Fuji | JPN | Right | Right | 6' 1" | 195 lbs | - |
| Sutton, Rod | LF | MSL D.C. Divided | 18 | 05/29/2045 | Los Angeles | USA | Right | Right | 5' 11" | 190 lbs | - |
| Sánchez, Júlio | C | Free Agent | 19 | 02/28/2044 | Mercedes | CRC | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Román | RP | Free Agent | 20 | 06/20/2043 | Los Dos Caminos | VEN | Right | Left | 5' 10" | 170 lbs | - |
