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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, José | SP | Sacramento Redlegs | 31 | 01/16/2031 | Duvergé | DOM | Left | Left | 6' 5" | 200 lbs | $11,000,000 |
| Salinas, Júlio | 2B | Sacramento Redlegs | 28 | 12/01/2033 | Higüey | DOM | Switch | Right | 6' 4" | 200 lbs | $280,000 |
| Sandoval, Dorian | SS | Montreal Machine | 25 | 12/09/2036 | Wichita | USA | Right | Right | 6' 2" | 200 lbs | - |
| Santos, Jorge | 1B | Bakersfield Nobles | 26 | 12/19/2035 | Managua | NCA | Right | Right | 6' 3" | 190 lbs | - |
| Santos, Pepe | 1B | Free Agent | 30 | 06/22/2032 | Pedro Brand | DOM | Left | Left | 6' 8" | 200 lbs | - |
| Sato, Yoshimasa | SP | Baton Rouge Brass | 29 | 07/16/2033 | Tonosho | JPN | Right | Right | 6' 3" | 210 lbs | $18,000,000 |
| Saucedo, Juan | 1B | Free Agent | 27 | 09/01/2034 | Araure | VEN | Left | Left | 6' 4" | 200 lbs | - |
| Saunders, David | LF | Free Agent | 33 | 08/26/2028 | Plymouth | USA | Left | Left | 6' 3" | 200 lbs | - |
| Scott, Pete | RP | Syracuse Squirrel Monkeys | 26 | 06/26/2036 | Houston | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sexton, Manny | RP | Bakersfield Nobles | 25 | 01/11/2037 | Athens | USA | Left | Right | 6' 6" | 220 lbs | - |
| Sherman, Paul | 1B | Kansas Rainbeaus | 23 | 05/30/2039 | Perryton | USA | Left | Right | 6' 5" | 210 lbs | - |
| Shinohara, Yoshitaka | SP | Sacramento Redlegs | 28 | 05/17/2034 | Seto | JPN | Right | Right | 6' 5" | 200 lbs | $280,000 |
| Silva, Leonardo | 2B | Free Agent | 27 | 08/07/2034 | Juana Díaz | PUR | Left | Right | 6' 2" | 200 lbs | - |
| Silva, Roberto | SP | Ellenburg Fighting Dachshunds | 33 | 06/13/2029 | Camagüey | CUB | Left | Left | 6' 4" | 195 lbs | - |
| Silver, Duke | SP | Montreal Machine | 29 | 07/20/2032 | San Francisco | USA | Left | Right | 5' 10" | 190 lbs | - |
| Sims, Mark | CL | Sacramento Redlegs | 23 | 02/23/2039 | New York | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sims, Nathan | SP | Jersey City Tritons | 36 | 10/05/2025 | Toledo | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sizemore, Chip | RP | Pennsauken Flyers | 31 | 07/11/2031 | Tacoma | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Derek | SS | Free Agent | 30 | 12/20/2031 | Miami | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Gary | RP | Montreal Machine | 23 | 08/09/2038 | Peoria | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Solís, Luis | RF | Sacramento Redlegs | 24 | 08/28/2037 | Almansa | ESP | Left | Left | 6' 2" | 195 lbs | - |
| Souza, Jorge | SP | Ellenburg Fighting Dachshunds | 41 | 09/01/2020 | Villa Vazquez | DOM | Right | Right | 6' 1" | 205 lbs | $10,600,000 |
| Spillman, Bill | 2B | Free Agent | 33 | 07/01/2029 | Chicago | USA | Switch | Right | 6' 0" | 200 lbs | - |
| Stanley, Robbie | SP | Syracuse Starks | 29 | 03/15/2033 | Atlanta | USA | Switch | Right | 6' 2" | 205 lbs | - |
| Stephens, Walt | RP | Pennsauken Flyers | 23 | 04/19/2039 | Youngstown | USA | Left | Left | 6' 5" | 195 lbs | $280,000 |
| Sterling, James | CF | Syracuse Squirrel Monkeys | 22 | 06/04/2040 | Caro | USA | Left | Right | 6' 1" | 170 lbs | - |
| Stone, Cliff | C | Bakersfield Nobles | 30 | 04/09/2032 | Slidell | USA | Right | Right | 6' 4" | 200 lbs | - |
| Strong, Bill | LF | Syracuse Starks | 33 | 06/28/2029 | Oakland | USA | Left | Left | 6' 2" | 200 lbs | $280,000 |
| Sullivan, David | SP | Bakersfield Nobles | 35 | 07/03/2027 | Wolverine Lake | USA | Switch | Right | 6' 2" | 200 lbs | $731,250 |
| Sullivan, Eric | C | Jersey City Tritons | 28 | 10/20/2033 | Sun City West | USA | Right | Right | 6' 4" | 200 lbs | - |
| Summers, Wayne | LF | Free Agent | 28 | 09/20/2033 | Peekskill | USA | Left | Left | 6' 1" | 195 lbs | - |
| Sánchez, Francisco | RP | Free Agent | 26 | 08/28/2035 | Caledonia | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sánchez, José | 2B | Montreal Machine | 31 | 10/18/2030 | Lagunillas | VEN | Right | Right | 6' 3" | 200 lbs | - |
