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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saginov, Amikishi | 3B | Northville Eclipse | 27 | 06/10/2036 | Rockaway Beach | USA | Left | Right | 6' 2" | 210 lbs | - |
| Salazar, Adrián | 2B | Asheville Highlanders | 27 | 12/25/2035 | Buckeye | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sankey, Joseph | SP | Lake Murray MotorBoaters | 23 | 07/25/2039 | Nassau | BAH | Right | Right | 6' 1" | 195 lbs | - |
| Santos, Ramón | SP | Billings Polar Bears | 22 | 02/16/2041 | San Bernardo | CHI | Left | Left | 5' 10" | 170 lbs | - |
| Santos, Raúl | SP | Ithaca Fighting Imps | 24 | 05/21/2039 | Tiquisate | GUA | Right | Left | 6' 2" | 200 lbs | - |
| Santos, Wilson | RP | Free Agent | 22 | 12/11/2040 | Belmopan | BLZ | Left | Left | 6' 0" | 175 lbs | - |
| Sardaneta, Salvador | CF | Asheville Highlanders | 27 | 05/19/2036 | Warwick | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sarpaneva, Sampo | RP | Free Agent | 26 | 12/29/2036 | Cegléd | HUN | Right | Right | 6' 1" | 195 lbs | - |
| Sassi, Kicham | RP | Northville Eclipse | 24 | 08/31/2038 | Pietermaritzburg | RSA | Left | Left | 6' 3" | 200 lbs | - |
| Scott, Bob | RP | Minnesota Loons | 23 | 06/02/2040 | Davis | USA | Right | Right | 6' 1" | 195 lbs | - |
| Scott, Paul | RP | Northville Eclipse | 28 | 02/01/2035 | Plymouth | USA | Left | Left | 6' 4" | 200 lbs | - |
| Scott, Tim | RP | Ithaca Fighting Imps | 26 | 09/14/2036 | Jackson | USA | Left | Left | 6' 4" | 200 lbs | - |
| Sears, John | 3B | Billings Polar Bears | 25 | 04/23/2038 | Phoenix | USA | Right | Right | 6' 0" | 180 lbs | - |
| Shagunov, Sasha | 2B | Northville Eclipse | 24 | 04/26/2039 | Moscow | RUS | Right | Right | 6' 0" | 190 lbs | - |
| Sheppard, Leonard | SP | Lake Murray MotorBoaters | 22 | 11/25/2040 | Sheboygan | USA | Switch | Right | 6' 4" | 205 lbs | - |
| Shields, Daniel | SP | Minnesota Loons | 27 | 04/04/2036 | Deerfield | USA | Switch | Right | 5' 11" | 180 lbs | - |
| Shuker, Alexander | SP | Minnesota Loons | 23 | 05/09/2040 | Savanna la Mar | JAM | Right | Right | 6' 7" | 205 lbs | - |
| Sims, Eric | RP | Asheville Highlanders | 28 | 11/24/2034 | Charleston | USA | Right | Right | 6' 2" | 200 lbs | - |
| Siu, Jing-sheng | 3B | Ithaca Fighting Imps | 25 | 08/02/2037 | Shanghai | CHN | Right | Right | 6' 2" | 205 lbs | - |
| Skinner, Brad | 3B | Lake Murray MotorBoaters | 25 | 04/28/2038 | Lockport | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Don | RP | Providence Pilgrims | 24 | 03/20/2039 | Germantown | USA | Left | Left | 6' 3" | 200 lbs | - |
| Smith, Tony | SP | Minnesota Loons | 25 | 06/20/2038 | Eagleville | USA | Right | Right | 6' 3" | 200 lbs | - |
| Solano, Guarçia | 1B | Billings Polar Bears | 21 | 10/14/2041 | Valencia | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Sosa, Lúcio | CF | Gulf Coast Turbeaus | 22 | 01/20/2041 | La Romana | DOM | Left | Left | 6' 5" | 200 lbs | - |
| Sosa, Salvador | 3B | Billings Polar Bears | 23 | 06/28/2040 | Glendale | USA | Right | Right | 6' 1" | 190 lbs | - |
| Steiner, Scott | LF | Gulf Coast Turbeaus | 22 | 05/18/2041 | Bay City | USA | Right | Right | 6' 1" | 185 lbs | - |
| Stevens, Brandon | CF | Gulf Coast Turbeaus | 21 | 08/15/2041 | Scranton | USA | Left | Left | 6' 3" | 200 lbs | - |
| Sutton, Gerald | RP | Asheville Highlanders | 22 | 12/17/2040 | San Jose | USA | Right | Right | 6' 0" | 190 lbs | - |
| Suárez, Manuel | SP | Northville Eclipse | 25 | 10/01/2037 | Yaritagua | VEN | Right | Right | 6' 0" | 195 lbs | - |
| Sáenz, Luis | 1B | Gulf Coast Turbeaus | 24 | 03/31/2039 | Metairie | USA | Right | Right | 6' 8" | 230 lbs | - |
| Sánchez, Orlando | CL | Providence Pilgrims | 24 | 11/04/2038 | Florida | PUR | Left | Right | 6' 0" | 200 lbs | - |
